The Histone H2A (acetyl K9) (4G2) Monoclonal Antibody from Bioss Inc. is a Rabbit Monoclonal antibody to H2A clustered histone 4, and H2A clustered histone 8. This antibody recognizes Human, Mouse, and Rat antigen. The Histone H2A (acetyl K9) (4G2) Monoclonal Antibody has been validated for the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling